De Lange Syndrome (Amsterdam Dwarfism)

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Cornelia De Lange Syndrome and Cochlear Implantation

Introduction: Literature regarding the different degrees of hearing loss in patients with Cornelia de Lange syndrome (CDLS) reports that half of the affected patients exhibit severe to profound sensorineural hearing loss. We present the first pre-school child with CDLS who underwent cochlear implantation for congenital profound sensorineural hearing loss.   Case Report: A 3-year-old boy with CD...

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Cornelia de Lange syndrome.

Cornelia de Lange syndrome (CdLS) is a rarely seen multisystem developmental disorder syndrome characterized by facial dysmorphia (arched eyebrows, synophrys, depressed nasal bridge, long philtrum, down-turned angles of the mouth), upper-extremity malformations, hirsutism, cardiac defects, growth and cognitive retardation, and gastrointestinal abnormalities. We present here a case of newborn ma...

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The De Lange Syndrome.

This is a book which clinical geneticists and those interested in malformations will enjoy looking at and reading. It is probably best bought together with the companion volumes rather than in isolation. It supplements but does not replace other illustrated catalogues which have been recently published on the malformation syndromes. Alzheimer's disease is a moderately infrequent form of preseni...

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Classical cornelia de lange syndrome.

SummaryThese two case reports illustrate the importance of doing a thorough dysmorphology examination for all so called "Multiple congenital anomalies" children and attempting to fit them into a recognized syndrome. Well over 2000 dysmorphic syndromes are now recognized and diagnosis of these children can be extremely difficult.

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Granulomatous rosacea in Cornelia de Lange syndrome.

It is true that mycological culture has a higher specificity, but it has lower sensitivity as compared to histopathology with periodic acid-Schiff staining (HP/ PAS).[1,2] HP/PAS is relatively quick, and a specificity of 72% cannot be overlooked.[3] In most cases, morphological aspect of the hyphae and/or spores can suggest the group to which pathogens belong.[3] In personal view of the authors...

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ژورنال

عنوان ژورنال: Proceedings of the Royal Society of Medicine

سال: 1973

ISSN: 0035-9157

DOI: 10.1177/003591577306601208